1 article found
KAT6A (lysine acetyltransferase 6A), also known as MOZ (monocytic leukemia zinc finger protein), is a MYST-family histone acetyltransferase essential for hematopoietic stem cell self-renewal, craniofacial development, and neurogenesis. Mutations in KAT6A cause a syndromic intellectual disability, and chromosomal translocations involving KAT6A are recurrent drivers of acute myeloid leukemia.