Results for "replication licensing"

KAT7 (HBO1 or MYST2) — a major histone H3K14 Acetyltransferase

KAT7 (lysine acetyltransferase 7), also known as HBO1 (histone acetyltransferase binding to ORC1) or MYST2, is a MYST-family enzyme and the principal acetyltransferase for histone H3 lysine 14 (H3K14ac) in mammals. Operating within BRPF- or JADE-containing complexes, KAT7 is required for DNA replication licensing, hematopoietic stem cell self-renewal, and embryonic development.